Green Fluorescent Protein

Green Fluorescent Protein (GFP) was originally isolated from the jellyfish Aequorea victoria and is used to fluorescently label cells and organisms, as well as specific proteins when incorporated into a chimeric “fluorescent fusion protein”.  Subsequently, numerous variants of GFP with altered characteristics, such as shifted excitation and emission spectra, have been generated, and fluorescent proteins from a variety of other organisms have been identified.  Research critical to the advent of GFP was awarded the Nobel Prize in Chemistry in 2008.